Overexpression of Myocardin-related transcription factor-A attenuated middle cerebral artery occlusion/reperfusion-induced apoptosis via the Mcl-1/Cyt C/cleaved caspase 3 pathway

Overexpression of Myocardin-related transcription factor-A attenuated middle cerebral artery occlusion/reperfusion-induced apoptosis via the Mcl-1/Cyt C/cleaved caspase 3 pathway

To investigate the effect of Myocardin-related transcription factor A (MRTF-A) on apoptosis induced by ischemic/reperfusion (I/R), middle cerebral artery occlusion/reperfusion (MCAO/R) in rats were applied to mimic I/R. The neurological deficit score, cerebral infarct size, cortical neuron apoptosis...

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Bibliographic Details
Main Authors: Zhi-Jun Yu, Jing Du, Wei Zhang, Shu-Qi Zhao, Wei Dong, Shi-Qiang Xu, Ling Hu, Zhen-Li Min, Qiong Yuan, Chunxiang Zhang, Xia-Min Hu
Format: Article
Language:English
Published: World Scientific Publishing 2019-11-01
Series:Journal of Innovative Optical Health Sciences
Subjects:
stroke
animal model
immunofluorescence staining
laser scanning confocal microscope
Online Access:http://www.worldscientific.com/doi/pdf/10.1142/S1793545819500226

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http://www.worldscientific.com/doi/pdf/10.1142/S1793545819500226

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