Altered Neuronal Dynamics in the Striatum on the Behavior of Huntingtin Interacting Protein 14 (HIP14) Knockout Mice

Altered Neuronal Dynamics in the Striatum on the Behavior of Huntingtin Interacting Protein 14 (HIP14) Knockout Mice

Huntington’s disease (HD), a neurodegenerative disorder caused by an expanded CAG repeat in the huntingtin gene, impairs information processing in the striatum, which, as part of the basal ganglia, modulates motor output. Growing evidence suggests that huntingtin interacting protein 14 (HIP14) contr...

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Bibliographic Details
Main Authors: Ana María Estrada-Sánchez, Scott J. Barton, George V. Rebec
Format: Article
Language:English
Published: MDPI AG 2013-11-01
Series:Brain Sciences
Subjects:
Huntington’s disease
huntingtin interacting protein 14
striatum
local field potentials
motor inflexibility
plus maze
palmitoylation
Online Access:http://www.mdpi.com/2076-3425/3/4/1588

Internet

http://www.mdpi.com/2076-3425/3/4/1588

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