Anticancer Diiron Vinyliminium Complexes: A Structure–Activity Relationship Study

Anticancer Diiron Vinyliminium Complexes: A Structure–Activity Relationship Study

A series of 16 novel diiron complexes of general formula [Fe<sub>2</sub>Cp<sub>2</sub>(CO)(μ-CO){μ-η<sup>1</sup>:η<sup>3</sup>-C(R′)C(R″)CN(R)(Y)}]CF<sub>3</sub>SO<sub>3</sub> (<b>2–7</b>), bearing different substitu...

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Bibliographic Details
Main Authors: Simona Braccini, Giorgia Rizzi, Lorenzo Biancalana, Alessandro Pratesi, Stefano Zacchini, Guido Pampaloni, Federica Chiellini, Fabio Marchetti
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Pharmaceutics
Subjects:
metal-based drugs
diiron complexes
cytotoxicity
ROS production
thioredoxin reductase inhibition
Online Access:https://www.mdpi.com/1999-4923/13/8/1158

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https://www.mdpi.com/1999-4923/13/8/1158

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