The PTEN–PI3K Axis in Cancer

The PI3K–AKT–mTOR signal transduction pathway regulates a variety of biological processes including cell growth, cell cycle progression and proliferation, cellular metabolism, and cytoskeleton reorganization. Fine-tuning of the phosphatidylinositol 3-kinase (PI3K) pathway signali...

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Bibliographic Details
Main Authors: Antonella Papa, Pier Paolo Pandolfi
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/9/4/153