Neuroinflammation in Multiple System Atrophy: Response to and Cause of alpha-Synuclein Aggregation

Neuroinflammation in Multiple System Atrophy: Response to and Cause of alpha-Synuclein Aggregation

Multiple system atrophy (MSA) is a progressive neurodegenerative disease presenting with combinations of autonomic dysfunction, parkinsonism, cerebellar ataxia and/or pyramidal signs. Oligodendroglial cytoplasmic inclusions rich in α-synuclein (α-syn) constitute the disease hallmark, accompanied by...

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Bibliographic Details
Main Authors: Bruno eDi Marco Vieira, Rowan Andrew Warren Radford, Roger S Chung, Gilles J. Guillemin, Dean Louis Pountney
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Multiple System Atrophy
Neuroinflammation
Astrogliosis
alpha-synuclien
Microgliosis
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00437/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00437/full

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