Calculation of the Median Lethal Dose and Low Lethal Dose Using the CombiStats Biometric Software

Calculation of the Median Lethal Dose and Low Lethal Dose Using the CombiStats Biometric Software

The median lethal dose (LD50) and low lethal dose (LD10) are calculated in acute toxicity studies, as well as during specific activity assessment of some medicines. The aim of the study was to develop a procedure for using CombiStats to calculate LD50 and LD10. The authors proposed a step-by-step al...

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Bibliographic Details
Main Authors: P. V. Shadrin, T. A. Batuashvili, L. V. Simutenko, N. P. Neugodova
Format: Article
Language:Russian
Published: OOO “Vashe Tsifrovoe Izdatelstvo” 2021-07-01
Series:Ведомости Научного центра экспертизы средств медицинского применения
Subjects:
median lethal dose
ld<sub>50</sub>
median effective dose
ed<sub>50</sub>
low lethal dose
ld<sub>10</sub>
combistats
biometric software
dose conversion
medicinal products
snake venom
Online Access:https://www.vedomostincesmp.ru/jour/article/view/344

Internet

https://www.vedomostincesmp.ru/jour/article/view/344

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