Characterization of stress degradation products of curcumin and its two derivatives by UPLC–DAD–MS/MS

Curcumin and its two derivatives of PB-3 and DY-1 were subjected to the forced degradation studies under the conditions of hydrolysis (acidic and alkaline), oxidation, photolysis, and thermal stress recommended by ICH Q1A (R2) by means of UPLC–DAD–MS/MS. Three analytes and their degradation products...

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Bibliographic Details
Main Authors: Linli Wang, Nan Lu, Longshan Zhao, Chao Qi, Weiyang Zhang, Jinhua Dong, Xiaohong Hou
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Arabian Journal of Chemistry
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535216000289