Carissa carandas Linn. fruit extract ameliorates gentamicin–induced nephrotoxicity in rats via attenuation of oxidative stress

Carissa carandas Linn. fruit extract ameliorates gentamicin–induced nephrotoxicity in rats via attenuation of oxidative stress

Objective: To elucidate the mechanism of action of methanolic extract of Carissa carandas fruits (MCCF) in attenuation of diabetic nephropathy using gentamicin induced nephrotoxicity model. Methods: Extract was daily administered to Sprague Dawley rats at doses of 100, 200 and 400 mg/kg for 8 days a...

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Bibliographic Details
Main Authors: Jayesh B. Dhodi, Deepavali R. Thanekar, Snehal N. Mestry, Archana R. Juvekar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-06-01
Series:Journal of Acute Disease
Subjects:
Gentamicin
Carissa carandas
Nephrotoxicity
Oxidative stress
Kidney hypertrophy
Online Access:http://www.sciencedirect.com/science/article/pii/S2221618915300238

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http://www.sciencedirect.com/science/article/pii/S2221618915300238

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