Fast Screening of Diol Impurities in Methoxy Poly(Ethylene Glycol)s (mPEG)s by Liquid Chromatography on Monolithic Silica Rods

Fast Screening of Diol Impurities in Methoxy Poly(Ethylene Glycol)s (mPEG)s by Liquid Chromatography on Monolithic Silica Rods

The determination of diol impurities in methoxy poly(ethylene glycol)s (mPEG)s is of high importance, e.g., in the area of pharmaceutical applications, since mPEGs are considered the gold standard—based on properties of biocompatibility, stealth effect against the immune system, and well-e...

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Bibliographic Details
Main Authors: Michaela Brunzel, Tobias C. Majdanski, Jürgen Vitz, Ivo Nischang, Ulrich S. Schubert
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Polymers
Subjects:
anionic ring-opening polymerization
MALDI-TOF-MS
monolith
PEGdiol
pharmaceutical PEG
reversed-phase chromatography
Online Access:https://www.mdpi.com/2073-4360/10/12/1395

Internet

https://www.mdpi.com/2073-4360/10/12/1395

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