Perampanel Confirms to Be Effective and Well-Tolerated as an Add-On Treatment in Patients With Brain Tumor-Related Epilepsy (PERADET Study)

Perampanel Confirms to Be Effective and Well-Tolerated as an Add-On Treatment in Patients With Brain Tumor-Related Epilepsy (PERADET Study)

Background: Epilepsy is one of the most common symptoms of brain tumors. It is often drug resistant and generally worsen patients' quality of life (QoL). Brain tumors release glutamate among other mediators, contributing to seizures onset, and this is accompanied by an increased AMPA receptors&...

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Bibliographic Details
Main Authors: Antonietta Coppola, Alessia Zarabla, Andrea Maialetti, Veronica Villani, Tatiana Koudriavtseva, Emilio Russo, Agostino Nozzolillo, Chiara Sueri, Vincenzo Belcastro, Simona Balestrini, Edoardo Ferlazzo, Diana Giannarelli, Leonilda Bilo, Marta Maschio
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Neurology
Subjects:
brain tumor-related epilepsy
perampanel
efficacy
tolerability
quality of life
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00592/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2020.00592/full

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