Inhibiting tumor necrosis factor‐alpha at time of induced intervertebral disc injury limits long‐term pain and degeneration in a rat model
Background Painful intervertebral disc (IVD) degeneration has tremendous societal costs and few effective therapies. Intradiscal tumor necrosis factor‐alpha (TNFα) is commonly associated with low back pain, but the direct relationship remains unclear. Purpose Treatment strategies for low back pain r...
Main Authors: | Thomas W. Evashwick‐Rogler, Alon Lai, Hironobu Watanabe, Jonathan M. Salandra, Beth A. Winkelstein, Samuel K. Cho, Andrew C. Hecht, James C. Iatridis |
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Format: | Article |
Language: | English |
Published: |
Wiley
2018-06-01
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Series: | JOR Spine |
Subjects: | |
Online Access: | https://doi.org/10.1002/jsp2.1014 |
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