Chemokine CCL4 Induced in Mouse Brain Has a Protective Role against Methylmercury Toxicity

Methylmercury (MeHg) is selectively toxic to the central nervous system, but mechanisms related to its toxicity are poorly understood. In the present study, we identified the chemokine, C-C motif Chemokine Ligand 4 (CCL4), to be selectively upregulated in the brain of MeHg-administered mice. We then...

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Bibliographic Details
Main Authors: Tsutomu Takahashi, Min-Seok Kim, Miyuki Iwai-Shimada, Masatake Fujimura, Takashi Toyama, Akira Naganuma, Gi-Wook Hwang
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Toxics
Subjects:
Online Access:http://www.mdpi.com/2305-6304/6/3/36