Magnesium acetyltaurate prevents retinal damage and visual impairment in rats through suppression of NMDA-induced upregulation of NF-κB, p53 and AP-1 (c-Jun/c-Fos)

Magnesium acetyltaurate prevents retinal damage and visual impairment in rats through suppression of NMDA-induced upregulation of NF-κB, p53 and AP-1 (c-Jun/c-Fos)

Magnesium acetyltaurate (MgAT) has been shown to have a protective effect against N-methyl-D-aspartate (NMDA)-induced retinal cell apoptosis. The current study investigated the involvement of nuclear factor kappa-B (NF-κB), p53 and AP-1 family members (c-Jun/c-Fos) in neuroprotection by MgAT against...

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Bibliographic Details
Main Authors: Lidawani Lambuk, Igor Iezhitsa, Renu Agarwal, Puneet Agarwal, Anna Peresypkina, Anna Pobeda, Nafeeza Mohd Ismail
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Neural Regeneration Research
Subjects:
ap-1 (c-jun/c-fos); electroretinography; magnesium acetyltaurate; neuroprotection; nf-κb; n-methyl-d-aspartate; object recognition tasks; p53; retinal excitotoxicity; retrograde labelling
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=11;spage=2330;epage=2344;aulast=Lambuk

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=11;spage=2330;epage=2344;aulast=Lambuk

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