Knockout of IRF7 Highlights its Modulator Function of Host Response Against Avian Influenza Virus and the Involvement of MAPK and TOR Signaling Pathways in Chicken

Interferon regulatory factor 7 (IRF7) is known as the master transcription factor of the type I interferon response in mammalian species along with IRF3. Yet birds only have IRF7, while they are missing IRF3, with a smaller repertoire of immune-related genes, which leads to a distinctive immune resp...

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Bibliographic Details
Main Authors: Tae Hyun Kim, Colin Kern, Huaijun Zhou
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/11/4/385