Neonatal and infant immunity for tuberculosis vaccine development: importance of age-matched animal models

Neonatal and infant immunity differs from that of adults in both the innate and adaptive arms, which are critical contributors to immune-mediated clearance of infection and memory responses elicited during vaccination. The tuberculosis (TB) research community has openly admitted to a vacuum of knowl...

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Bibliographic Details
Main Authors: Laylaa Ramos, Joan K. Lunney, Mercedes Gonzalez-Juarrero
Format: Article
Language:English
Published: The Company of Biologists 2020-09-01
Series:Disease Models & Mechanisms
Subjects:
Online Access:http://dmm.biologists.org/content/13/9/dmm045740