CD300f epitopes are specific targets for acute myeloid leukemia with monocytic differentiation

CD300f epitopes are specific targets for acute myeloid leukemia with monocytic differentiation

Antibody‐based therapy in acute myeloid leukemia (AML) has been marred by significant hematologic toxicity due to targeting of both hematopoietic stem and progenitor cells (HSPCs). Achieving greater success with therapeutic antibodies requires careful characterization of the potential target molecul...

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Bibliographic Details
Main Authors: Edward Abadir, Robin E. Gasiorowski, Kaitao Lai, Fiona Kupresanin, Adelina Romano, Pablo A. Silveira, Tsun‐Ho Lo, Phillip D. Fromm, Marina L. Kennerson, Harry J. Iland, P. Joy Ho, P. Mark Hogarth, Kenneth Bradstock, Derek N.J. Hart, Georgina J. Clark
Format: Article
Language:English
Published: Wiley 2019-10-01
Series:Molecular Oncology
Subjects:
acute myeloid leukemia
antibody epitopes
CD300f
cell surface targeting
isoform expression
monoclonal antibodies
Online Access:https://doi.org/10.1002/1878-0261.12549

Internet

https://doi.org/10.1002/1878-0261.12549

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