Roles of APOBEC3A and APOBEC3B in Human Papillomavirus Infection and Disease Progression

Roles of APOBEC3A and APOBEC3B in Human Papillomavirus Infection and Disease Progression

The apolipoprotein B messenger RNA-editing, enzyme-catalytic, polypeptide-like 3 (APOBEC3) family of cytidine deaminases plays an important role in the innate immune response to viral infections by editing viral genomes. However, the cytidine deaminase activity of APOBEC3 enzymes also induces somati...

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Bibliographic Details
Main Authors: Cody J. Warren, Joseph A. Westrich, Koenraad Van Doorslaer, Dohun Pyeon
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:Viruses
Subjects:
Keywords: papillomavirus
human papillomavirus (HPV)
apolipoprotein B messenger RNA-editing, enzyme-catalytic, polypeptide-like 3 (APOBEC3)
innate immunity
virus restriction
cancer mutagenesis
cancer progression
somatic mutation
virus evolution
Online Access:https://www.mdpi.com/1999-4915/9/8/233

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https://www.mdpi.com/1999-4915/9/8/233

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