DENV NS1 and MMP-9 cooperate to induce vascular leakage by altering endothelial cell adhesion and tight junction.

DENV NS1 and MMP-9 cooperate to induce vascular leakage by altering endothelial cell adhesion and tight junction.

Dengue virus (DENV) is a mosquito-borne pathogen that causes a spectrum of diseases including life-threatening dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). Vascular leakage is a common clinical crisis in DHF/DSS patients and highly associated with increased endothelial permeabilit...

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Bibliographic Details
Main Authors: Pan Pan, Geng Li, Miaomiao Shen, Zhenyang Yu, Weiwei Ge, Zizhao Lao, Yaohua Fan, Keli Chen, Zhihao Ding, Wenbiao Wang, Pin Wan, Muhammad Adnan Shereen, Zhen Luo, Xulin Chen, Qiwei Zhang, Luping Lin, Jianguo Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-07-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008603

Internet

https://doi.org/10.1371/journal.ppat.1008603

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