Influence of DNMT genotype on global and site specific DNA methylation patterns in neonates and pregnant women.

This study examines the relationship between common genetic variation within DNA methyltransferase genes and inter-individual variation in DNA methylation. Eleven polymorphisms spanning DNMT1 and DNMT3B were genotyped. Global and gene specific (IGF2, IGFBP3, ZNT5) DNA methylation was quantified by L...

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Bibliographic Details
Main Authors: Catherine Potter, Jill McKay, Alexandra Groom, Dianne Ford, Lisa Coneyworth, John C Mathers, Caroline L Relton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3788139?pdf=render