CYBA Gene Polymorphisms and Adverse Outcomes in Acute Kidney Injury: A Prospective Cohort Study

CYBA Gene Polymorphisms and Adverse Outcomes in Acute Kidney Injury: A Prospective Cohort Study

Background: NADPH oxidase is an important enzyme involved in the generation of reactive oxygen species in acute kidney injury (AKI). Its key subunit, p22phox, is encoded by the highly polymorphic CYBA gene. Methods: We examined the associations of CYBA gene polymorphisms across the CYBA locus (rs885...

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Bibliographic Details
Main Authors: Mary C. Perianayagam, Hocine Tighiouart, Caroline M. Nievergelt, Daniel T. O’Connor, Orfeas Liangos, Bertrand L. Jaber
Format: Article
Language:English
Published: Karger Publishers 2011-10-01
Series:Nephron Extra
Subjects:
Acute kidney injury
CYBA
Gene polymorphisms
Haplotype
Isoprostane
NADPH oxidase
Nitrotyrosine
NOX
p22phox
Online Access:http://www.karger.com/Article/FullText/333017

Internet

http://www.karger.com/Article/FullText/333017

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