Split-cre complementation indicates coincident activity of different genes in vivo.

Cre/LoxP recombination is the gold standard for conditional gene regulation in mice in vivo. However, promoters driving the expression of Cre recombinase are often active in a wide range of cell types and therefore unsuited to target more specific subsets of cells. To overcome this limitation, we de...

Full description

Bibliographic Details
Main Authors: Johannes Hirrlinger, Anja Scheller, Petra G Hirrlinger, Beate Kellert, Wannan Tang, Michael C Wehr, Sandra Goebbels, Andreas Reichenbach, Rolf Sprengel, Moritz J Rossner, Frank Kirchhoff
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19172189/?tool=EBI