Up to date on cholesterol 7 alpha-hydroxylase (CYP7A1) in bile acid synthesis

Cholesterol 7 alpha-hydroxylase (CYP7A1, EC1.14) is the first and rate-limiting enzyme in the classic bile acid synthesis pathway. Much progress has been made in understanding the transcriptional regulation of CYP7A1 gene expression and the underlying molecular mechanisms of bile acid feedback regul...

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Bibliographic Details
Main Authors: John Y.L. Chiang, Jessica M. Ferrell
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2020-06-01
Series:Liver Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2542568420300210