The AGC Kinase YpkA Regulates Sphingolipids Biosynthesis and Physically Interacts With SakA MAP Kinase in Aspergillus fumigatus

Sphingolipids (SL) are complex lipids and components of the plasma membrane which are involved in numerous cellular processes, as well as important for virulence of different fungal pathogens. In yeast, SL biosynthesis is regulated by the “AGC kinases” Ypk1 and Ypk2, which also seem to connect the S...

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Main Authors: João Henrique Tadini Marilhano Fabri, Naiane Lima Godoy, Marina Campos Rocha, Mansa Munshi, Tiago Alexandre Cocio, Marcia Regina von Zeska Kress, Taicia Pacheco Fill, Anderson Ferreira da Cunha, Maurizio Del Poeta, Iran Malavazi
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Microbiology
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Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.03347/full