Use of net reclassification improvement (NRI) method confirms the utility of combined genetic risk score to predict type 2 diabetes.

<h4>Background</h4>Recent genome-wide association studies (GWAS) identified more than 70 novel loci for type 2 diabetes (T2D), some of which have been widely replicated in Asian populations. In this study, we investigated their individual and combined effects on T2D in a Chinese populati...

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Bibliographic Details
Main Authors: Claudia H T Tam, Janice S K Ho, Ying Wang, Vincent K L Lam, Heung Man Lee, Guozhi Jiang, Eric S H Lau, Alice P S Kong, Xiaodan Fan, Jean L F Woo, Stephen K W Tsui, Maggie C Y Ng, Wing Yee So, Juliana C N Chan, Ronald C W Ma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24376643/pdf/?tool=EBI