X Inactivation and Escape: Epigenetic and Structural Features

X Inactivation and Escape: Epigenetic and Structural Features

X inactivation represents a complex multi-layer epigenetic mechanism that profoundly modifies chromatin composition and structure of one X chromosome in females. The heterochromatic inactive X chromosome adopts a unique 3D bipartite structure and a location close to the nuclear periphery or the nucl...

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Bibliographic Details
Main Authors: He Fang, Christine M. Disteche, Joel B. Berletch
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
X chromosome
X inactivation
3D-structure
LncRNAs
escape gene
epigenetics
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2019.00219/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2019.00219/full

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