Tissue expression of lactate transporters (MCT1 and MCT4) and prognosis of malignant pleural mesothelioma (brief report)

Tissue expression of lactate transporters (MCT1 and MCT4) and prognosis of malignant pleural mesothelioma (brief report)

Abstract Background Malignant pleural mesothelioma (MPM) is an aggressive neoplasm of the pleura, mainly related to asbestos exposure. As in other solid tumors, malignant cells exhibit high glucose uptake and glycolytic rates with increased lactic acid efflux into the interstitial space. Lactate tra...

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Bibliographic Details
Main Authors: Irene Dell’Anno, Elisa Barone, Luciano Mutti, Doris M. Rassl, Stefan J. Marciniak, Roberto Silvestri, Stefano Landi, Federica Gemignani
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Journal of Translational Medicine
Subjects:
Malignant pleural mesothelioma (MPM)
MCT1
MCT4
Basigin (CD147)
Immunohistochemistry (IHC)
Tissue microarray (TMA)
Online Access:http://link.springer.com/article/10.1186/s12967-020-02487-6

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http://link.springer.com/article/10.1186/s12967-020-02487-6

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