Incomplete influenza A virus genomes occur frequently but are readily complemented during localized viral spread

The genome of influenza is often incomplete in infected cells, but the implications for infection remain unclear. Here, Jacobs et al. show that an average of 3.6 particles is necessary for productive infection and that coinfection supports efficient complementation within a host but not upon transmi...

Full description

Bibliographic Details
Main Authors: Nathan T. Jacobs, Nina O. Onuoha, Alice Antia, John Steel, Rustom Antia, Anice C. Lowen
Format: Article
Language:English
Published: Nature Publishing Group 2019-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11428-x