SARS-CoV-2 crosses the blood–brain barrier accompanied with basement membrane disruption without tight junctions alteration

SARS-CoV-2 crosses the blood–brain barrier accompanied with basement membrane disruption without tight junctions alteration

Abstract SARS-CoV-2 has been reported to show a capacity for invading the brains of humans and model animals. However, it remains unclear whether and how SARS-CoV-2 crosses the blood–brain barrier (BBB). Herein, SARS-CoV-2 RNA was occasionally detected in the vascular wall and perivascular space, as...

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Bibliographic Details
Main Authors: Ling Zhang, Li Zhou, Linlin Bao, Jiangning Liu, Hua Zhu, Qi Lv, Ruixue Liu, Wei Chen, Wei Tong, Qiang Wei, Yanfeng Xu, Wei Deng, Hong Gao, Jing Xue, Zhiqi Song, Pin Yu, Yunlin Han, Yu Zhang, Xiuping Sun, Xuan Yu, Chuan Qin
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-021-00719-9

Internet

https://doi.org/10.1038/s41392-021-00719-9

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