The efficacy of dihydroartemisinin-piperaquine and artemether-lumefantrine with and without primaquine on Plasmodium vivax recurrence: A systematic review and individual patient data meta-analysis.

The efficacy of dihydroartemisinin-piperaquine and artemether-lumefantrine with and without primaquine on Plasmodium vivax recurrence: A systematic review and individual patient data meta-analysis.

<h4>Background</h4>Artemisinin-based combination therapy (ACT) is recommended for uncomplicated Plasmodium vivax malaria in areas of emerging chloroquine resistance. We undertook a systematic review and individual patient data meta-analysis to compare the efficacies of dihydroartemisinin...

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Main Authors: Robert J Commons, Julie A Simpson, Kamala Thriemer, Tesfay Abreha, Ishag Adam, Nicholas M Anstey, Ashenafi Assefa, Ghulam R Awab, J Kevin Baird, Bridget E Barber, Cindy S Chu, Prabin Dahal, André Daher, Timothy M E Davis, Arjen M Dondorp, Matthew J Grigg, Georgina S Humphreys, Jimee Hwang, Harin Karunajeewa, Moses Laman, Kartini Lidia, Brioni R Moore, Ivo Mueller, Francois Nosten, Ayodhia P Pasaribu, Dhelio B Pereira, Aung P Phyo, Jeanne R Poespoprodjo, Carol H Sibley, Kasia Stepniewska, Inge Sutanto, Guy Thwaites, Tran T Hien, Nicholas J White, Timothy William, Charles J Woodrow, Philippe J Guerin, Ric N Price
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-10-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1002928

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https://doi.org/10.1371/journal.pmed.1002928

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