Immunosuppressive Microenvironment Revealed by Immune Cell Landscape in Pre-metastatic Liver of Colorectal Cancer

Immunosuppressive Microenvironment Revealed by Immune Cell Landscape in Pre-metastatic Liver of Colorectal Cancer

Background: Colorectal cancer, the fourth leading cause of cancer mortality, is prone to metastasis, especially to the liver. The pre-metastatic microenvironment comprising various resident stromal cells and immune cells is essential for metastasis. However, how the dynamic evolution of immune compo...

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Bibliographic Details
Main Authors: Dongqiang Zeng, Miaohong Wang, Jiani Wu, Siheng Lin, Zilan Ye, Rui Zhou, Gaofeng Wang, Jianhua Wu, Huiying Sun, Jianping Bin, Yulin Liao, Nailin Li, Min Shi, Wangjun Liao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
immunosuppressive microenvironment
pre-metastatic niche
MDSC
metabolism
colorectal cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.620688/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.620688/full

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