The Effects of Bergamot Polyphenolic Fraction, <i>Cynara cardunculus</i>, and <i>Olea europea</i> L. Extract on Doxorubicin-Induced Cardiotoxicity

The Effects of Bergamot Polyphenolic Fraction, <i>Cynara cardunculus</i>, and <i>Olea europea</i> L. Extract on Doxorubicin-Induced Cardiotoxicity

Doxorubicin is an anthracycline that is commonly used as a chemotherapy drug due to its cytotoxic effects. The clinical use of doxorubicin is limited due to its known cardiotoxic effects. Treatment with anthracyclines causes heart failure in 15–17% of patients, resulting in mitochondrial dysfunction...

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Bibliographic Details
Main Authors: Jessica Maiuolo, Irene Bava, Cristina Carresi, Micaela Gliozzi, Vincenzo Musolino, Federica Scarano, Saverio Nucera, Miriam Scicchitano, Francesca Bosco, Stefano Ruga, Maria Caterina Zito, Francesca Oppedisano, Roberta Macri, Annamaria Tavernese, Rocco Mollace, Vincenzo Mollace
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Nutrients
Subjects:
doxorubicin
rat embryonic cardiomyoblasts
Bergamot Polyphenolic Fraction
oleuropein
<i>Cynara cardunculus</i>
endoplasmic reticulum
Online Access:https://www.mdpi.com/2072-6643/13/7/2158

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https://www.mdpi.com/2072-6643/13/7/2158

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