NhaA Na+/H+ antiporter mutants that hardly react to the membrane potential.

pH and Na+ homeostasis in all cells requires Na+/H+ antiporters. The crystal structure, obtained at pH 4, of NhaA, the main antiporter of Escherichia coli, has provided general insights into an antiporter mechanism and its unique pH regulation. Here, we describe a general method to select various Nh...

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Bibliographic Details
Main Authors: Dudu Alkoby, Abraham Rimon, Maral Budak, Miyer Patino-Ruiz, Octavian Călinescu, Klaus Fendler, Etana Padan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3974702?pdf=render