House dust mite major allergens Der p 1 and Der p 5 activate human airway-derived epithelial cells by protease-dependent and protease-independent mechanisms

<p>Abstract</p> <p>House dust mite allergens (HDM) cause bronchoconstriction in asthma patients and induce an inflammatory response in the lungs due to the release of cytokines, chemokines and additional mediators. The mechanism how HDM components achieve this is largely unknown. T...

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Bibliographic Details
Main Authors: Timmerman J André B, Tamm Michael, Kauffman Henk F, Borger Peter
Format: Article
Language:English
Published: BMC 2006-03-01
Series:Clinical and Molecular Allergy
Online Access:http://www.clinicalmolecularallergy.com/content/4/1/5