Wnt/β-Catenin Signaling Pathway Governs a Full Program for Dopaminergic Neuron Survival, Neurorescue and Regeneration in the MPTP Mouse Model of Parkinson’s Disease

Wnt/β-Catenin Signaling Pathway Governs a Full Program for Dopaminergic Neuron Survival, Neurorescue and Regeneration in the MPTP Mouse Model of Parkinson’s Disease

Wingless-type mouse mammary tumor virus (MMTV) integration site (Wnt) signaling is one of the most critical pathways in developing and adult tissues. In the brain, Wnt signaling contributes to different neurodevelopmental aspects ranging from differentiation to axonal extension, synapse formation, n...

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Bibliographic Details
Main Author: Bianca Marchetti
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:International Journal of Molecular Sciences
Subjects:
Parkinson’s disease
cell death
dopaminergic neurons
Wnt/β-catenin signaling
glia–neuron cross-talk
neurodegeneration
neuroprotection
neurorepair
Online Access:https://www.mdpi.com/1422-0067/19/12/3743

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https://www.mdpi.com/1422-0067/19/12/3743

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