Fighting the Monster: Applying the Host Damage Framework to Human Central Nervous System Infections

The host damage-response framework states that microbial pathogenesis is a product of microbial virulence factors and collateral damage from host immune responses. Immune-mediated host damage is particularly important within the size-restricted central nervous system (CNS), where immune responses ma...

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Bibliographic Details
Main Authors: Anil A. Panackal, Kim C. Williamson, Diederik van de Beek, David R. Boulware, Peter R. Williamson
Format: Article
Language:English
Published: American Society for Microbiology 2016-03-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/7/1/e01906-15