Inhibitory effect of carvedilol on human hepatic stellate cell activation and fibrosis induced by platelet-derived growth factor-BB and related mechanisms of action

ObjectiveTo investigate the effect of carvedilol on the migration, invasion and fibrosis of human hepatic stellate cells, as well as related signaling pathways and mechanisms. MethodsHuman hepatic stellate cell line LX-2 was treated with different concentrations of carvedilol (0, 1, 2, 5, and 10 μmo...

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Bibliographic Details
Main Authors: LI Zhen, LIU Bin
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Hepatology 2017-03-01
Series:Linchuang Gandanbing Zazhi
Subjects:
Online Access:http://www.lcgdbzz.org/qk_content.asp?id=8067