Cambogin is preferentially cytotoxic to cells expressing PDGFR.

Cambogin is preferentially cytotoxic to cells expressing PDGFR.

Platelet-derived growth factor receptors (PDGFRs) have been implicated in a wide array of human malignancies, including medulloblastoma (MB), the most common brain tumor of childhood. Although significant progress in MB biology and therapeutics has been achieved during the past decades, MB remains a...

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Bibliographic Details
Main Authors: Ze Tian, Jie Shen, Fengfei Wang, Peigen Xiao, Junshan Yang, Hetian Lei, Andrius Kazlauskas, Isaac S Kohane, Erxi Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3119700?pdf=render

Internet

http://europepmc.org/articles/PMC3119700?pdf=render

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