Distribution of CYP2D6 alleles and phenotypes in the Brazilian population.

The CYP2D6 enzyme is one of the most important members of the cytochrome P450 superfamily. This enzyme metabolizes approximately 25% of currently prescribed medications. The CYP2D6 gene presents a high allele heterogeneity that determines great inter-individual variation. The aim of this study was t...

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Bibliographic Details
Main Authors: Deise C Friedrich, Júlia P Genro, Vinicius A Sortica, Guilherme Suarez-Kurtz, Maria Elizabete de Moraes, Sergio D J Pena, Andrea K Ribeiro dos Santos, Marco A Romano-Silva, Mara H Hutz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4203818?pdf=render