Distribution of CYP2D6 alleles and phenotypes in the Brazilian population.
The CYP2D6 enzyme is one of the most important members of the cytochrome P450 superfamily. This enzyme metabolizes approximately 25% of currently prescribed medications. The CYP2D6 gene presents a high allele heterogeneity that determines great inter-individual variation. The aim of this study was t...
Main Authors: | Deise C Friedrich, Júlia P Genro, Vinicius A Sortica, Guilherme Suarez-Kurtz, Maria Elizabete de Moraes, Sergio D J Pena, Andrea K Ribeiro dos Santos, Marco A Romano-Silva, Mara H Hutz |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4203818?pdf=render |
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