Mechanisms of tRNA-derived fragments and tRNA halves in cancer treatment resistance

Mechanisms of tRNA-derived fragments and tRNA halves in cancer treatment resistance

Abstract The tRNA-derived fragments (tRFs) and tRNA halves (tiRNAs) are newly discovered noncoding RNAs in recent years. They are derived from specific cleavage of mature and pre-tRNAs and expressed in various cancers. They enhance cell proliferation and metastasis or inhibit cancer progression. Man...

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Bibliographic Details
Main Authors: Yue Zhang, Huizhu Qian, Jing He, Wen Gao
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Biomarker Research
Subjects:
tRNA-derived fragments
tRNA halves
Cancer
Drug resistance
Biomarker
Online Access:http://link.springer.com/article/10.1186/s40364-020-00233-0

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http://link.springer.com/article/10.1186/s40364-020-00233-0

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