TNF-α antagonist attenuates systemic lipopolysaccharide-induced brain white matter injury in neonatal rats

TNF-α antagonist attenuates systemic lipopolysaccharide-induced brain white matter injury in neonatal rats

Abstract Background Systemic inflammation is an important risk factor for neurodevelopmental impairments in preterm infants. Premyelinating oligodendrocytes are main building blocks of white matter in preterm infants and vulnerable to oxidative stress and excitotoxic stress. Tumour necrosis factor-α...

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Bibliographic Details
Main Authors: Seung Han Shin, Ee-Kyung Kim, Kyung-yup Lee, Han-Suk Kim
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Neuroscience
Subjects:
Newborn
White matter injury
Systemic inflammation
TNF-α antagonist
Online Access:http://link.springer.com/article/10.1186/s12868-019-0529-1

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http://link.springer.com/article/10.1186/s12868-019-0529-1

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