Immune Response of A Novel ATR-AP205-001 Conjugate Anti-hypertensive Vaccine

Abstract We developed a virus-like particle (VLP)-based therapeutic vaccine against angiotensin II receptor type 1, ATR-AP205-001, which could significantly reduce the blood pressure and protect target organs of hypertensive animals. In this study, we focused on the immunological effect and safety o...

Full description

Bibliographic Details
Main Authors: Xiajun Hu, Yihuan Deng, Xiao Chen, Yanzhao Zhou, Hongrong Zhang, Hailang Wu, Shijun Yang, Fen Chen, Zihua Zhou, Min Wang, Zhihua Qiu, Yuhua Liao
Format: Article
Language:English
Published: Nature Publishing Group 2017-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-12996-y