Glycogen synthase kinase3 beta phosphorylates serine 33 of p53 and activates p53's transcriptional activity

<p>Abstract</p> <p>Background</p> <p>The p53 protein is activated by genotoxic stress, oncogene expression and during senescence, p53 transcriptionally activates genes involved in growth arrest and apoptosis. p53 activation is regulated by post-translational modificatio...

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Bibliographic Details
Main Authors: Price Brendan D, Turenne Gaetan A
Format: Article
Language:English
Published: BMC 2001-07-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/2/12