Effective melanoma immunotherapy in mice by the skin-depigmenting agent monobenzone and the adjuvants imiquimod and CpG.

Effective melanoma immunotherapy in mice by the skin-depigmenting agent monobenzone and the adjuvants imiquimod and CpG.

Presently melanoma still lacks adequate treatment options for metastatic disease. While melanoma is exceptionally challenging to standard regimens, it is suited for treatment with immunotherapy based on its immunogenicity. Since treatment-related skin depigmentation is considered a favourable progno...

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Bibliographic Details
Main Authors: Jasper G van den Boorn, Debby Konijnenberg, Esther P M Tjin, Daisy I Picavet, Nico J Meeuwenoord, Dmitri V Filippov, J P Wietze van der Veen, Jan D Bos, Cornelis J M Melief, Rosalie M Luiten
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2869359?pdf=render

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http://europepmc.org/articles/PMC2869359?pdf=render

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