Side-by-side comparison of gene-based smallpox vaccine with MVA in nonhuman primates.

Orthopoxviruses remain a threat as biological weapons and zoonoses. The licensed live-virus vaccine is associated with serious health risks, making its general usage unacceptable. Attenuated vaccines are being developed as alternatives, the most advanced of which is modified-vaccinia virus Ankara (M...

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Bibliographic Details
Main Authors: Joseph W Golden, Matthew Josleyn, Eric M Mucker, Chien-Fu Hung, Peter T Loudon, T C Wu, Jay W Hooper
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3409187?pdf=render