Maternal Risk for Down Syndrome Is Modulated by Genes Involved in Folate Metabolism

Studies have shown that the maternal risk for Down syndrome (DS) may be modulated by alterations in folate metabolism. The aim of this study was to evaluate the influence of 12 genetic polymorphisms involved in folate metabolism on maternal risk for DS. In addition, we evaluated the impact of these...

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Bibliographic Details
Main Authors: Bruna Lancia Zampieri, Joice Matos Biselli, Eny Maria Goloni-Bertollo, Hélio Vannucchi, Valdemir Melechco Carvalho, José Antônio Cordeiro, Érika Cristina Pavarino
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.3233/DMA-2011-0869