Oncolytic vesicular stomatitis virus expressing interferon-σ has enhanced therapeutic activity

Oncolytic viruses are known to stimulate the antitumor immune response by specifically replicating in tumor cells. This is believed to be an important aspect of the durable responses observed in some patients and the field is rapidly moving toward immunotherapy. As a further means to engage the immu...

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Bibliographic Details
Main Authors: Marie-Claude Bourgeois-Daigneault, Dominic Guy Roy, Theresa Falls, Kwame Twumasi-Boateng, Lauren Elizabeth St-Germain, Monique Marguerie, Vanessa Garcia, Mohammed Selman, Victoria Ann Jennings, Jessica Pettigrew, Sally Amos, Jean-Simon Diallo, Brad Nelson, John Cameron Bell
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Molecular Therapy: Oncolytics
Online Access:http://www.sciencedirect.com/science/article/pii/S237277051630033X