Danhong injection enhances the therapeutic effect of mannitol on hemispheric ischemic stroke by ameliorating blood-brain barrier disruption

Danhong injection enhances the therapeutic effect of mannitol on hemispheric ischemic stroke by ameliorating blood-brain barrier disruption

Mannitol, a representative of hyperosmolar therapy, is indispensable for the treatment of malignant cerebral infarction, but its therapeutic effect is limited by its exacerbation of blood-brain barrier (BBB) disruption. This study was to explore whether Danhong injection (DHI), a standardized produc...

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Bibliographic Details
Main Authors: Miaolin Zeng, Huifen Zhou, Yu He, Haixia Du, Junjun Yin, Yongchun Hou, Jiaqi Zhu, Yangyang Zhang, Chongyu Shao, Jiehong Yang, Haitong Wan
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Ischemic stroke
Mannitol
Danhong injection
Blood-brain barrier
Energy metabolism
Matrix metalloprotein
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221008313

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http://www.sciencedirect.com/science/article/pii/S0753332221008313

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