Acquisition of cancer stem cell capacities after spontaneous cell fusion

Abstract Background Cancer stem/Initiating cell (CS/IC) hypothesis argues that CS/ICs are responsible of tumour initiation, drug resistance, metastasis or disease relapse. Their detection in several cancers supports this concept. However, their origin is still misunderstood. Cell fusion is shown to...

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Bibliographic Details
Main Authors: Candice Merle, Pauline Lagarde, Lydia Lartigue, Frédéric Chibon
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-021-07979-2