Natural molecule Munronoid I attenuates LPS-induced acute lung injury by promoting the K48-linked ubiquitination and degradation of TAK1

Acute lung injury (ALI) is a severe lung disease with limited therapeutic strategies. Munronoid I, a limonoid, which is extracted and purified from Munronia sinica, exhibits effective anti-neoplastic activities. In this study, we attempted to determine the anti-inflammatory effects of Munronoid I us...

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Bibliographic Details
Main Authors: Xingyu Ma, Xiaoli Li, Qianqian Di, Xibao Zhao, Ruihan Zhang, Yue Xiao, Ping Sun, Haimei Tang, Jiazheng Quan, Weilie Xiao, Weilin Chen
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221003280